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IMPACT OF POST-IMPLANT EDEMA ON DOSE COVERAGE IN PROSTATE BRACHYTHERAPY: CAN IMPLANT QUALITY BE ASSESSED ON DAY 0?
Frank M. Waterman and Adam P. Dicker
Supported in part by P30 CA 56036-03 (NCI)

Department of Radiation Oncology, Kimmel Cancer Center, Jefferson Medical College, Thomas Jefferson University Hospital, Philadelphia, PA 19107

Conclusions:
Dose coverage is relatively insensitive to post-implant edema in peripheral loaded prostate I-125 implants planned with a margin. Although, dose coverage is underestimated by the day 0 CT scan, the underestimation seldom exceeds 10% and suboptimal implants can be readily identified on day 0. Our results show that 70 %, 80%, 85%, and 90% coverage on day 0 can be expected to increase to 80 + 8 %, 87 + 7 %, 90 + 6 %, and 94 + 4 %, respectively, by day 46 and indicate that the 30 day standard for implant quality, D90 > 140 Gy, is equivalent to D85 > 140 Gy on day 0.

Purpose | Materials and Methods | Results | Conclusions
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