
Forward
Versus Inverse Treatment Planning for Head and Neck Tumors that Surround Critical Normal
Structures
Greg Bednarz, Ph.D., M. Saiful Huq, Ph.D., John W. Sweet, Ph.D., Samuel
Hughes, M.D., Walter J. Curran, Jr., M.D., Pramila Rani Anne, M.D., James M. Galvin, D.Sc.
Department of Radiation Oncology, Kimmel Cancer Center, Jefferson Medical
College, Thomas Jefferson University Hospital, Philadelphia, PA 19107
Materials and Methods:
Dose inhomogeneity for treatment plans generated by inverse techniques often exceeds the 5
to 10% encountered in traditional treatment planning. This report investigates the
hypothesis that forward planning can produce similar dose distributions when normal
constraints on dose homogeneity are lifted. A second hypothesis is that the forward
approach results in intensity maps that are simplified relative to inverse planning. The
forward planning technique described here (implemented on the CMS/FOCUSä
planning system) starts with conformal fields at nine equally spaced, co-planar gantry
angles. For these same gantry angles, additional fields are added that only partially
irradiate the target so that invaginations are created within the dose distributions
produced by the conformal fields. The width and depth of the desired invagination
determine the size and relative weight of the added fields. Simple rules for determining
these parameters are discussed. In order to improve the overall dose homogeneity, missing
tissue compensators are used for all fields. Instead of using any physical beam modifiers,
compensator thicknesses generated with the FOCUS system are converted to intensities and
combined with the added field segments to produce a final intensity map for each gantry
angle. These final intensity distributions are compared to those produced for the same
patient with the NOMOS/CORVUSä inverse-planning system with
the optimization restricted to use the nine gantry angles. This comparison is accomplished
by segmenting the final intensity maps and counting the total number of sub-fields as a
measure of the complexity of the distributions. Additionally, the amount of the dose that
is delivered as an open conformal field is determined. Dose-Volume Histograms (DVHs) for
the PTV and all critical structures are also compared for the two planning techniques. The
comparison was carried out for a total of 5 cases for patients with head and neck lesions
that surround the spinal cord. In each case, the optimization included a boost volume.
Purpose | Materials
and Methods | Results | Conclusions
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