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Selected Clinical Trials from the Jefferson Department of Radiation Oncology
FY 2004-05

Abbreviated Study  Title

Type of Study

P.I.(s)

RT/Temodar/cpt-11 for GBM

RTOG Phase II

Curran

Whole breast vs. partial breast RT for Breast CA

RTOG/NSABP Phase III

Anne/Rudoler

Neoadjuvant chemo-RT for rectal CA

RTOG Phase IIR

Anne

High dose vs. moderate dose RT for prostate CA

RTOG Phase III

Valicenti

Postop RT + chemo + C-225 for head/neck CA

RTOG Phase IIR

Machtay

RT + chemo + C-225 for inoperable lung CA

RTOG Phase II

Werner-Wasik

Prophylactic brain irradiation for lung CA

RTOG Phase III

Werner-Wasik

 

 

 

ABC Breath-hold irradiation for Left-sided breast Cancer*

Investigator-initiated Phase II

Anne

RT + hormones + Samarium radioisotope therapy for Prostate Cancer.

Investigator-initiated Phase I

Valicenti

RT + Epothilone radiosensitizing chemo for CNS or head and neck Cancer.

Investigator-initiated Phase I

Dicker

RT +Capecitabine + cpt-11 multimodality therapy for rectal cancer.

Investigator-initiated Phase I

Anne

Randomized trial of Immobilization for CNS Image Guided Radiation Therapy (Stereotactic RT).

Investigator-initiated Phase III

Bednarz/Machtay

Stereotactic irradiation + Gefitinib for inoperable lung cancer.

Investigator-initiated Phase I

Werner-Wasik

 

 

 

RT +/- Temodar for Brain metastases from lung cancer.

Corporate (Schering) Phase III

Curran

Benzydamine for prevention of RT mucositis for patients with head and neck cancer.*

Corporate (McNeil) Phase III

Machtay

* = Non-therapeutic clinical trial


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