 Frank M. Waterman, Ph.D.
Professor, Medical Physics Division, Department of Radiation Oncology, Thomas
Jefferson UniversityE-mail: frank.waterman@mail.tju.edu
Research Interests
Brachytherapy:
- Effect of edema on the post-implant dosimetric evaluation of permanent prostate implants
- Dose-Response of permanent prostate implants
- CT imaging of the prostate
- Intravascular radiation for restinosis
- Dosimetric comparison of intersitial implant and electron boost therapy in the treatment
of early stage breast cancer
- Development of software for CT-based brachytherapy.
Hyperthermia: Response of human tumor blood flow to hyperthermia.
EDUCATION:
| Institution and Location |
Degree |
Year(s) |
Field of Study |
| University of Chicago, Chicago, IL |
Postdoc |
1975-77 |
Medical Physics |
| Kent State University, Kent, OH |
Postdoc |
1972-75 |
Physics |
| Clarkson University, Potsdam NY |
Ph.D. |
1973 |
Physics |
| Clarkson University, Potsdam, NY |
M.S. |
1969 |
Physics |
| Hartwick College, Oneonta, NY |
B.A. |
1960 |
Physics |
Certification
American Board of Radiology - Radiological Physics, 1982
Research and Professional Experience
| 1972-1975 |
Research Associate, Kent State University, Kent, Ohio |
| 1975-1977 |
Postdoctoral Trainee, University of Chicago, Illinois |
| 1977-1979 |
Research Associate (Assistant Professor), University of Chicago |
| 1979-1985 |
Assistant Professor (Medical Physics) Dept. of Radiation Oncology &
Nuclear Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania |
| 1985-1991 |
Associate Professor (Medical Physics) Department of Radiation Oncology
and Nuclear Medicine Thomas Jefferson University Hospital, Philadelphia, Pennsylvania |
| 1991 to Present |
Professor (Medical Physics) Department of Radiation Oncology, Thomas
Jefferson University Hospital, Philadelphia, Pennsylvania |
Selected Publications
Waterman, F.M., Kuchnir, F.T. Skaggs, L.S., Bewely, D.K., Page, S. and
Attix, F.H. The Use of 10B to enhance the tumor dose in fast-neutron therapy. Phys Med
Biol 23:592-602, 1978.
Waterman, F.M., Kuchnir, F.T., Skaggs, L.S., Kouzes, R.T., Moore, W.H. Energy
dependence of the neutron sensitivity of C-CO2, Mg-Ar, and TE-TE ionization chambers. Phys
Med Biol 24:721-3,1979.
Waterman, F.M., Kuchnir, F.T., Skaggs, L.S., Kouzes, R.T. and Moore, W.H.
Neutron spectra. Med Phys 6:160-61, 1979.
Waterman, F.M., Kuchnir, F.T., Skaggs, L.S., Kouzes, R.T., Moore, W.H. Neutron
spectra from 35 and 46 MeV protons, 16 and 28 MeV deuterons, and 44 MeV 3He ions on thick
beryllium. Med Phys 6:432-35, 1979.
Waterman, F.M. , Nerlinger, R.E., Paglione R.W., Heating characteristics
of a 100 MHz ridged waveguide. (Abstract) Med Phys 10(4):526, 1983.
Waterman, F.M., Nerlinger, R.E. The effect of bolus on the distribution
ofspecific absorption rate at 915 MHz. Med Phys 11:381, 1984.
Waterman, F.M. , The response of thermometer probes inserted into catheters. Med
Phys 12:368-372, 1985.
Waterman, F.M. , Evaluation of the Luxtron Model 2000 fluoroptic
thermometer.Med. Phys. 12:515, 1985. (Abstract).
Waterman, F. M., Nerlinger, R.E. The effect of coupling materials on specific
absorption rate distributions at 915 MHz. Med Phys 13:391-95, 1986.
Waterman, F.M., Nerlinger, R.E., Moylan, D.J., Leeper, D.B. Response of
human tumor blood flow to local hyperthermia. Int J Radiat Oncol Biol Phys. 13, 75-82,
1987.
Waterman, F.M., Tupchong, L., Matthews, J., Nerlinger, R.R.,
Determination of the transport of thermal energy by conduction in perfused tissue. Heat
Transfer in Bioengineering and Medicine, HTD Vol. 95/BED Vol. 7, edited by J.C. Chato,T.E.
Diller, and R.B. Roemer (American Society of Mechanical Engineers, N.Y.) pp. 37-43, 1987.
Waterman, F.M., Measurement of Perfusion in Human Tumors. Biological,
Physical and Clinical Aspects of Hyperthermia, AAPM Monograph No. 16, edited by B.R.
Paliwal, F.W. Hetzel, and M.W. Dewhirst (American Institute of Physics, N.Y.) pp. 182-207.
Waterman, F.M. Determination of the temperature artifact during ultrasonic
heating. Hyperthermic Oncol. 1988. Vol. 1. Edited by Tsutomu, S. And Masao, S. (Taylor and
Francis, N.Y.) pp. 657-658, 1988.
Waterman, F.M., Tupchong, L. Mattews, J. Nerlinger, R.E., Mechanisms of heat
removal during hyperthermia. Int J Radiat Oncol Biol Phys 17(5), 1049-1055, 1989.
Waterman, F.M., Determination of the temperature artifact during ultrasound
hyperthermia, Inc. J. Hyperthermia, 6(1), 131-142, 1990.
Waterman, F.M., and Leeper, J.B., Temperature artifacts produced by
thermocouples used in conjunction with 1 and 3 MHZ ultrasound. Int J Hyperthermia, 6(2),
383-399, 1990.
Waterman, F.M., Tupchong, L., Nerlinger, R., Matthews, J., Blood flow in human
tumors during local hyperthermia. Int J Rad Oncol Biol Phys 20(5), 1255-1262, 1991.
Waterman, F.M. and Tupchong, L., A modified thermal clearance technique
for determination of blood flow during local hyperthermia. Int J Hyperthermia 7(5),
719-733, 1991.
Waterman, F.M. Estimation of temperature artifact from a short interruption in
ultrasonic power. Int. J.Hyperthermia.
Engin, K., Tuphong, L., Waterman, F.M., Hoh, L.L., McFarlane, J.D.,
Nerlinger, R.E., Leeper, D.B., 8(3), 395-400, 1992. Thermotherapy for advanced soft-tissue
sarcoma. Endocurie, Hypertherm. Oncol. 8, 19-26, 1992.
Engin, K., Tupchong, L., Waterman, F.M., Nerlinger, R.E., and Leeper,
D.B., Optimization of hyperthermia with CT scanning. Int. J. Hyperthermia. 8, 855-864,
1992.
Engin, K. Tupchong, L. Komarnicky, L. Waterman, F.M., Alexander, G.A.,
Nerlinger, R.E., Leeper, D.B. (1993) Randomized trial of once-weekly vs. twice weekly
hyperthermia treatments in thermoradiotherapy of superfical tumors. Int. J. Hyperthermia.
9:327-340.
Engin, K., Tuphong, L., Waterman, F.M., Moylan, D.J., Nerlinger, R.E., and
Leeper, D.B., Hyperthermia and radiation in advanced melanoma. Int. J. Radiation Oncol.
Biol. Phys. 25,87-94, 1993.
Engin, K., Leeper, D.B., Tupchong, L., Waterman, F.M., Mansfield, C.M.
(1993) Thermoradiation therapy for superficial malignant tumors. Cancer 72:287-296.
Engin, K., Tupchong, L. Waterman, F.M., McFarlane, J.D., Hoh, L.L. and Leeper
D.B. (1993) Thermoradiotherapy with combined instersitital and external hyperthermia in
advanced tumors in the head and neck with depth > 3 cm. Int. J. Hyperthermia 9:645-654.
Engin, K., Tupchong, L., Waterman, F.M., Komarnicky, L., Mansfield, C.M.,
Hussain, N., Hoh, L.L., McFarlane, J.D., Leeper, D.B., Multiple field hyperthermia
combined with radiotherapy in advanced carcinoma of the breast. Int.J. Hyperthermia 10,
587-603, 1994.
Engin, K., Tupchong, L., Waterman, F.M.,Cater, J.R., McFarlane, J.D.,
Hoh, L.L.and Leeper, D.B., Predictive factors for skin reactions in patients treated with
thermoradiotherapy, Int. J. Hyperthermia 11, 357-364, 1995.
Hoh, L.L. and Waterman, F.M., Use of manganin-constantan thermocouples in
thermometry units designed for copper-constantan thermocouples. Int. J. Hyperthermia 11,
131-138, 1995.
Waterman, F.M. and Hoh, L.L., Recommended revision in the RTOG
thermometry guidelines for hyperthermia administered by ultrasound. Int. J. Hyperthermia
11, 121-130, 1995.
Engin, K., Leeper, D.B., Tupchong, L., Waterman, F.M., Thermoradiotherapy in the
management of superficial malignant tumors. Clinical Cancer Research 1, 139-145, 1995.
Waterman, F.M. and Strubler, K.A. Absorbed dose determination for
interstitiaI-125 boost therapy. Med Phys 10:155-158, 1983.
Waterman, F.M. and Holcomb, D.E., Dose distributions produced by a
shielded vaginal cylinder using a high-activity iridium-192 source. Med. Phys. 21,
101-106, 1994.
Yu, Y., Waterman, F.M., Suntharalingam, N., Schulsinger, A: Limitations
of the minimum peripheral dose as a parameter for dose specification in permanent I-125
prostate implants. Int. J. Rad.Onc.Biol.Phys. 20(3), 711-725, 1996.
Saw, C.B., Waterman, F.M., Meigooni, A., Darb, L.J., Instrumentation and
equipment, in Principles and Practice of Brachytherapy. Ed. Nag, S., Futura Publishing
Co., Armonk, N.Y., 1997
Waterman, F.M., Mansfield, C.M., Komarnicky, L., Anne', P.R. , Corn, B.W.,
Suntharalingam, N. A dosimetry system for Iridium-192 interstitial breast implants
performed at the time of lumpectomy. Submitted to Int.J. Rad. Oncol. Biol. Phys. 37(1),
229-235, 1997.
Waterman, F.M., Yue, N., Reisinger, S., Dicker, A., Corn, B.W., Effect of edema
on the post-implant dosimetry of an I-125 prostate implant. Int. J. Radia. Oncol. Biol.
Phys. 33(2), 335-339, 1997.
Mishra, V., Waterman, F.M., Suntharalingham, N., Anisotropy of an 192 iridium
high dose rate source measured with a miniature ionization chamber. Med. Phys. 24,
751-756, 1997.
Valicenti, R.K., Waterman, F.M., Croce, R.J., Corn, B., Suntharalingham, N.,
Curran, W.J., Efficient CT simulation of the four-field technique for conformal
radiotherapy of prostate carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 37, 953-957, 1997.
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