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Developmental Immunology

Program Overview

Timothy Manser, Ph.D., Program Director

Recent years have seen a revolution in understanding of the basic workings of the immune system. This revolution has been driven by advances in technology, particularly in the areas of molecular genetics, "reversed" genetics, and information processing, as well as by creative integration of these new technologies with more "classical" approaches. As a consequence, the next generation of Immunologists will be poised to elucidate the molecular and cellular mechanisms underlying numerous human disease processes. However, this will require an extensive education not only in modern techniques and the scientific method, but also in approaches and areas that appear tangential to the field at present.

It is the purpose of the predoctoral and postdoctoral Training Program in Developmental Immunology to provide such an education to individuals with solid science backgrounds. The Training Program utilizes a select group of faculty from The Kimmel and Fox Chase Cancer Centers that share overlapping interests related to the development of immune responses and resistance to infectious diseases.

Predoctoral students within this Training Program take a comprehensive course in Foundations of Biomedical Science in their first semester, followed by six advanced courses inImmunology and Microbiology in their first two years of matriculation. Students are also required to take three elective introductory courses focused on topics such as Genetics, Biochemistry, Developmental Biology, or Cell Biology. Depending upon their research interests, students can also choose advanced electives from a wide variety of offerings provided by other departments. In addition, students participate and attend the Immunology and Microbial Pathogenesis Journal Club, Seminar Series, and Work in Progress sessions on a weekly basis. Students are required to do three rotations in the laboratories of research preceptors with interests in Immunology or Infectious Disease before choosing a preceptor and direction for thesis work. Students periodically present seminars throughout their training and are required to present their research progress to their Thesis Research Committee twice a year.

This Ph.D. program is open to individuals who hold a Bachelor's degree from an accredited institution, as well as individuals who already hold or will obtain other professional degrees (e.g. M.D.,D.O., D.V.M., or D.D.S.). Acceptance is based on grade point average, GRE scores, research experience, letters of recommendation, and an interview.

For the postdoctoral program, applicants must hold a Ph.D., or equivalent doctoral degree, and acceptance will depend upon past research excellence, educational experience and career goals. The intent of this part of the program is to facilitate the development of scientists capable of performing and directing creative and productive independent research in Immunology.

Preceptors in the Developmental Immunology Training Program

Resident at TJU and the KCC

Tim Manser, PhD, Professor, Microbiology and Immunology, Director
Kishore Alugupalli, PhD, Assistant Professor, Microbiology and Immunology
Laurence C. Eisenlohr, VMD, PhD, Professor, Microbiology and Immunology
Matthias J. Schnell, PhD, Professor, Microbiology and Immunology
Linda D. Siracusa, PhD, Associate Professor, Microbiology and Immunology
Yuri Sykulev, MD, PhD, Assistant Professor, Microbiology and Immunology
Jianke Zhang, PhD, Assisant Professor, Microbiology and Immunology
Bruno Calabretta, MD, PhD, Professor, Cancer Biology

Resident at the FCCC

Kerry S. Campbell, PhD, Member, Immunology Group
Richard R. Hardy, PhD, Associate Director, Senior Member, Immunology Group
Kyoko Hayakawa, MD, PhD, Member, Immunology Group
Dietmar J. Kappes, PhD, Member, Immunology Group
Glenn F. Rall, PhD, Member, Virology Group
Luis J. Sigal, DVM, PhD, Associate Member, Virology Group
David L. Wiest, PhD, Member, Immunology Group

For program information contact:
Joanne Balitzky, Graduate Programs Coordinator, KCC
Telephone: 215-503-6687
Fax: 215-923-1098