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Cancer Biologist Steven B. McMahon, Ph.D., Joins Kimmel Cancer Center at Jefferson

(PHILADELPHIA) Steven B. McMahon, Ph.D., has been named associate professor in the Department of Cancer Biology at Jefferson Medical College of Thomas Jefferson University in Philadelphia and at the Kimmel Cancer Center at Jefferson.

Dr. McMahon comes to Jefferson after spending the last seven years at The Wistar Institute in Philadelphia, where he served as both an assistant professor from 1999 to 2005 and an associate professor from 2005 to 2006, respectively, in the Gene Expression and Regulation Program.

From 1994 to 1999, Dr. McMahon worked as a visiting research fellow at Princeton University, studying the biochemical and molecular basis of transformation by the MYC proto-oncogene.

His research focuses on the two most commonly mutated master regulatory genes, MYC and p53, that are critical to cancer progression. His team is trying to gain an understanding of precisely how MYC and p53 first become activated during cancer and how that activation lets them control the expression of target genes that are involved in causing full blown disease.

“Dr. McMahon has made several seminal discoveries in cancer research which focus on tractable targets for patients’ therapies in the future,” says Kimmel Cancer Center director Richard Pestell, M.D., Ph.D., professor and chair of cancer biology at Jefferson Medical College. “Jefferson and the Kimmel Cancer Center are fortunate to be attracting internationally recognized scientists of Steve’s caliber during this exciting time of new growth and invigoration at the institution.”

A recipient of many awards, Dr. McMahon has been honored by several national organizations for his research. He received the American Association for Cancer Research Gertrude Elion Award in 2000 and won a W.W. Smith Research Foundation Award in 2002. Dr. McMahon also received the Elsa Pardee Research Foundation Award in 2004 and was recently named a Research Scholar of the American Cancer Society.

Dr. McMahon has lectured widely and his research has appeared in a number of prestigious, peer-reviewed publications including Science, Cell, and Molecular Cell.

His editorial responsibilities include serving as associate editor of Cancer Research, and he is a permanent member of the National Cancer Institute’s Advisory Committee on Manpower and Training.

Dr. McMahon received a Bachelor of Science degree in biology from Albright College in 1982 and a Master of Science degree in physiology from Temple University in 1984. He earned his doctor of philosophy in immunology from the University of Pennsylvania in 1994, focusing on the transcriptional regulation of cell cycle progression in lymphocytes.


Published: 01/07
Contact: Steve Benowitz or Jackie Kozloski
Thomas Jefferson University
After Hours: 215/955-6060